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   Effect of prophylactic CPAP in very low birth weight infants in South America  
   
نویسنده Zubizarreta J R ,Lorch S A ,Marshall G ,D'Apremont I ,Tapia J L
منبع journal of perinatology - 2016 - دوره : 36 - شماره : 8 - صفحه:629 -634
چکیده    Objective:the objective of this study was to examine the effect of prophylactic continuous positive airway pressure (cpap) on infants born in 25 south american neonatal intensive care units affiliated with the neocosur neonatal network using novel multivariate matching methods.study design:a prospective cohort was constructed of infants with a birth weight 500 to 1500 g born between 2005 and 2011 who clinically were eligible for prophylactic cpap. patients who received prophylactic cpap were matched to those who did not on 23 clinical and sociodemographic variables (n=1268). outcomes were analyzed using the mcnemar’s test.results:infants not receiving prophylactic cpap had higher mortality rates (odds ratio (or)=1.69, 95% confidence interval (ci) 1.17, 2.46), need for any mechanical ventilation (or=1.68, 95% ci 1.33, 2.14) and death or bronchopulmonary dysplasia (bpd) (or=1.47, 95% ci 1.09, 1.98). the benefit of prophylactic cpap varied by birth weight and gender.conclusions:the implementation of this process was associated with a significant improvement in survival and survival free of bpd.
آدرس Columbia University, Division of Decision, Department of Statistics, USA, The Children's Hospital of Philadelphia, Division of Neonatology, Department of Pediatrics, USA. University of Pennsylvania School of Medicine, USA. University of Pennsylvania, USA, Pontificia Universidad Catolica de Chile, Department of Statistics, Department of Public Health, Chile, Pontificia Universidad Catolica de Chile, Division de Pediatria, Departamento de Neonatologia, Chile, Pontificia Universidad Catolica de Chile, Division de Pediatria, Departamento de Neonatologia, Chile
 
     
   
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