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   Inhaled nitric oxide use in preterm infants in California neonatal intensive care units  
   
نویسنده Handley S C ,Steinhorn R H ,Hopper A O ,Govindaswami B ,Bhatt D R ,Meurs K P Van ,Ariagno R L ,Gould J B ,Lee H C
منبع journal of perinatology - 2016 - دوره : 36 - شماره : 8 - صفحه:635 -639
چکیده    Objective:to describe inhaled nitric oxide (ino) exposure in preterm infants and variation in neonatal intensive care unit (nicu) use.study design:this was a retrospective cohort study of infants, 22 to 33+6/7 weeks of gestational age (ga), during 2005 to 2013. analyses were stratified by ga and included population characteristics, ino use over time and hospital variation.results:of the 65 824 infants, 1718 (2.61%) received ino. infants, 22 to 24+6/7 weeks of ga, had the highest incidence of ino exposure (6.54%). community nicus (n=77, median hospital use rate 0.7%) used less ino than regional nicus (n=23, median hospital use rate 5.8%). in 22 to 24+6/7 weeks of ga infants, the median rate in regional centers was 10.6% (hospital interquartile range 3.8% to 22.6%).conclusion:ino exposure varied with ga and hospital level, with the most use in extremely premature infants and regional centers. variation reflects a lack of consensus regarding the appropriate use of ino for preterm infants.
آدرس Children’s Hospital of Philadelphia, Department of Pediatrics, USA, University of California, Department of Pediatrics, USA, Loma Linda University, Department of Pediatrics, USA, Santa Clara Valley Medical Center, Department of Pediatrics, USA, Department of Pediatrics, Kaiser Permanente, USA, Stanford University, Department of Pediatrics, USA, Stanford University, Department of Pediatrics, USA. Oak Ridge Institute for Research and Education (ORISE), USA. US Food and Drug Administration, USA, Stanford University, Department of Pediatrics, USA. California Perinatal Quality Care Collaborative (CPQCC), USA, Stanford University, Department of Pediatrics, USA. California Perinatal Quality Care Collaborative (CPQCC), USA
 
     
   
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