Predictive value of fetal hepatic biometry for birth weight and cord blood markers in gestational diabetes

Objective:the objective of this study is to evaluate third-trimester fetal liver biometry, to predict birth weight and cord markers at birth in diabetic pregnancies.study design:fetal liver biometry (liver diameters, area and volume) was obtained between 32 and 34 weeks. a blood sample was obtained from cord after birth. receiver operating characteristic (roc) curve models were evaluated for 75th and 90th birth weight percentile. univariate and multivariate models were used.result:all the hepatic diameters, area and sectional volume demonstrated significant differences in both birth weight percentile ⩾75 and ⩾90. all roc curves showed significant values. a significant association was observed for all measurements with birth weight. in multivariate model, liver area volume gave significant values for predicting birth weight. cord leptin, c-peptide and ferritin were related to fetal hepatic size.conclusion:the hepatic changes in gestational diabetes were valid to predict birth weight and metabolic changes at birth.