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Risk stratification for congenital diaphragmatic hernia by factors within 24 h after birth
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نویسنده
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Terui K ,Nagata K ,Kanamori Y ,Takahashi S ,Hayakawa M ,Okuyama H ,Inamura N ,Yoshida H ,Taguchi T ,Usui N
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منبع
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journal of perinatology - 2017 - دوره : 37 - شماره : 7 - صفحه:805 -808
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چکیده
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Objective:to establish a simple risk stratification system for patients with congenital diaphragmatic hernia (cdh) based on postnatal information within 24 h after birth.study design:a multi-institutional retrospective cohort study was conducted including 348 neonates who had isolated cdh born between 2006 and 2010. based on the two most powerful variables for 90-day survival selected by multivariate analyses, a risk stratification system was established.results:multiple logistic regression analysis identified two adverse prognostic factors: an apgar score at 1 min (ap1) of 0–4 (odds ratio (or) 3.3, p=0.004), and a best oxygenation index (oi) ⩾8.0 (or 11.4, p<0.001). based on a combinations of these two factors, patients were classified into three risk categories. the 90-day survival rates in categories 1–3 were 100, 88 and 52%, respectively (p<0.001).conclusion:our simple risk stratification system based on ap1 and best oi was capable of predicting mortality well.
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آدرس
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Chiba University, Department of Pediatric Surgery, Japan, Kyushu University, Department of Pediatric Surgery, Japan, National Center for Child Health and Development, Division of Surgery, Japan, National Center for Child Health and Development, Department of Maternal-Fetal and Neonatal Medicine, Japan, Nagoya University Hospital, Japan, Osaka University Graduate School of Medicine, Department of Pediatric Surgery, Japan, Kindai University, Department of Pediatrics, Japan, Chiba University, Department of Pediatric Surgery, Japan, Kyushu University, Department of Pediatric Surgery, Japan, Osaka Medical Center and Research Institute for Maternal and Child Health, Department of Pediatric Surgery, Japan
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Authors
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