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Urticaria due to antihistamines
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نویسنده
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morillas l.s. ,pérez-ezquerra p.r. ,martos m.r. ,sanz m.l. ,martínez j.j.l.
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منبع
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journal of investigational allergology and clinical immunology - 2011 - دوره : 21 - شماره : 1 - صفحه:66 -68
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چکیده
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H1-antihistamines are probably the most frequently used drugs in allergic diseases,with widely established effi cacy,tolerance,and safety. we report a patient with urticaria due to ingestion of ebastine and fexofenadine. skin prick tests,patch tests,and basophil activation tests with the implicated drugs and antihistamines from other families were negative. the oral challenges with the implicated antihistamines and other antihistamines tested were positive,but the patient tolerated an oral challenge with cetirizine. we present a patient with urticaria nduced by different antihistamines in whom the diagnosis was established by oral challenge. the mechanism of sensitization remains unclear. © 2011 esmon publicidad.
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کلیدواژه
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Adverse drug reaction; Antihistamines; Cross-reactivity; Urticaria
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آدرس
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allergology department,hospital central de la cruz roja,madrid, Spain, allergology department,hospital central de la cruz roja,madrid, Spain, allergology department,hospital central de la cruz roja,madrid, Spain, allergology department,clínica universidad de navarra,pamplona, Spain, allergology department,hospital central de la cruz roja,madrid, Spain
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Authors
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