Correlation between visit-to-visit and short-term blood pressure variability calculated using different methods and glomerular filtration rate

The aim of this study was to explore the correlation between visit-to-visit and short-term blood pressure variability (bpv), including systolic bpv (sbpv) and diastolic bpv (dbpv), calculated using different methods, and the glomerular filtration rate (gfr) in a late, middle-aged population. using cluster sampling, we randomly selected retired employees of the kailuan group who were ⩾60 years and participated in a third health examination for 24-h ambulatory blood pressure monitoring and inspection. among the 3064 randomly selected observation subjects, 2464 were included based on the criteria. bpv was calculated using s.d., coefficient of variation (cv, s.d./mean), variability independent of mean (vim, s.d./meanx) and bpv ratio (bpvr, s.d. (sbpv)/s.d. (dbpv)). multivariate linear regression was used to analyse the correlation between estimated gfr (egfr) and bpv calculated using different methods. the mean age of 2464 subjects was 67.4±6.1 years, with 1667 male subjects (67.7%). a total of 2104 cases were included in the visit-to-visit bpv group, and 1382 in the short-term bpv group. sbpv calculated using different methods showed statistically significant increasing trends for the sbp versus all s.d. and short-term bpvr. there was a significant, positive correlation between the visit-to-visit and short-term bpv calculated using different methods, which were all negatively correlated with egfr (p<0.05). multivariate linear regression analysis showed that, with correction for possible confounding factors, sbpv (24-h s.d., cv and vim, and daytime cv and night time cv) and all dbpv demonstrated negative linear relationships with egfr (p<0.05).