The genomic landscape of human immune-mediated diseases

As the methodology of genetic detection has developed rapidly in recent years, through techniques such as genome-wide association studies (gwas) and the secondary generation of sequencing, we are able to view the genomic landscape more clearly. it is well known that genes have a vital role in the pathogenesis of immune-mediated diseases (imds), which could provide important insight into new clinical therapeutic targets. here, we review the genomic landscape of imds and analyse overlapping loci between diseases. there may be a need for more epigenetics studies to aid in the understanding of the transition from genotype to phenotype.