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Genetics of long-QT syndrome
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نویسنده
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Nakano Yukiko ,Shimizu Wataru
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منبع
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journal of human genetics - 2016 - دوره : 61 - شماره : 1 - صفحه:51 -55
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چکیده
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Congenital long qt syndrome (lqts) is an inherited arrhythmia syndrome characterized by a prolonged qt interval in the 12-lead ecg, torsades de pointes and not negligible prevalence of sudden cardiac death. the genetic testing plays an important role in the diagnosis of lqts. a total of 15 genes have been reported for autosomal-dominant forms of romano–ward-type congenital lqts and 2 genes for autosomal-recessive forms of the jervell and lange–nielsen syndrome. in this review, we summarize the recent advances in genetics of lqts and briefly describe forward perspectives of lqts investigation.
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آدرس
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Hiroshima University, Division of Frontier Medical Science, Department of Cardiovascular Medicine, Japan, Nippon Medical School, Department of Cardiovascular Medicine, Japan
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Authors
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