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   Effect of genomics-related literacy on non-communicable diseases  
   
نویسنده Nakamura Sho ,Narimatsu Hiroto ,Katayama Kayoko ,Sho Ri ,Yoshioka Takashi ,Fukao Akira ,Kayama Takamasa
منبع journal of human genetics - 2017 - دوره : 62 - شماره : 9 - صفحه:839 -846
چکیده    Recent progress in genomic research has raised expectations for the development of personalized preventive medicine, although genomics-related literacy of patients will be essential. thus, enhancing genomics-related literacy is crucial, particularly for individuals with low genomics-related literacy because they might otherwise miss the opportunity to receive personalized preventive care. this should be especially emphasized when a lack of genomics-related literacy is associated with elevated disease risk, because patients could therefore be deprived of the added benefits of preventive interventions; however, whether such an association exists is unclear. association between genomics-related literacy, calculated as the genomics literacy score (gls), and the prevalence of non-communicable diseases was assessed using propensity score matching on 4646 participants (males: 1891; 40.7%). notably, the low-gls group (score below median) presented a higher risk of hypertension (relative risk (rr) 1.09, 95% confidence interval (ci) 1.03–1.16) and obesity (rr 1.11, 95% ci 1.01–1.22) than the high-gls group. our results suggest that a low level of genomics-related literacy could represent a risk factor for hypertension and obesity. evaluating genomics-related literacy could be used to identify a more appropriate population for health and educational interventions.
آدرس Yamagata University Faculty of Medicine, Japan. Kanagawa Cancer Center Research Institute, Cancer Prevention and Control Division, Japan, Kanagawa Cancer Center Research Institute, Cancer Prevention and Control Division, Japan. Kanagawa Cancer Center, Department of Genetic Medicine, Japan, Kanagawa Cancer Center Research Institute, Cancer Prevention and Control Division, Japan, Yamagata University Graduate School of Medicine, Department of Public Health, Japan, Yamagata University Faculty of Medicine, Japan, Yamagata University Graduate School of Medicine, Department of Public Health, Japan, Yamagata University Faculty of Medicine, Department of Advanced Cancer Science, Japan
 
     
   
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