A Comparison of the Anesthesia Efficacy of Articaine and Articaine plus Morphine for Buccal Infiltration in Mandibular Posterior Teeth with Irriversible Pulpitis

Background: successful local anesthesia is the bedrock of pain control in endodontics. pain control is essential to reduce fear and anxiety associated with endodontic procedure. the aim of study was, identifying and comparison of the anesthesia efficacy of articaine and articaine plus morphine for buccal infiltration in mandibular posterior teeth with irriversible pulpitis.materials and methods: this randomized double-blind clinical trial included 75 patients with symtomatically irreversible pulpitis in mandibular teeth. patient divided 3 groups randomly received either a buccal infiltration of 4% articaine with 1:100000 epinephrine or articaine morphine with 1:100000 epinephrine or ian block of 2% lidocaine with 1:800000 epinephrine. self-reported pain response was recorded on vas scale before and after local anesthetic injection during access preparation. for statistical analysis were used ?2, t-test, one way anova and mann whitney.results: statistical analysis result show success rate of articaine (68%), articaine morphine (52%) and lidocaine (64%). there was no statistically difference in the success rate between groups.conclusion: addition of the morphine to articaine does not increase success rate of buccal infiltration.