The Influence of Nine-Week Intensive Aerobic Exercises, Calcium and Vitamin D Supplementation on the Metabolic Response of Bone Formation Biomarkers

Background: the purpose of the study is to analyze the impact of 9-week intensive aerobic exercises and the calcium and vitamin d supplement intake on the indicators which show bone formation in young women.materials and methods: 44 non-athletic women in their thirties (27.18±3.65) were studied randomly in four groups: 1) exercise, 2) calcium and vitamin d supplement, 3) exercise and supplement, and 4) control. the subjects exercised three sessions a week for 9 weeks, each session lasted 30-45 minutes. the blood and urinary samples were collected from the experimental and control groups while they fasted either before or after exercise program. the concentration of alkaline phosphates and procollagen i, c terminal (picp) had been measured using dgkc and hplc techniques, respectively. the collected data had been combined with the statistical t-tests and were analyzed by ancova (p < 0.05).results: significant increasing of alp and picp was observed in exercise group (p=0.001) and exercise + supplement group (p=0.001). in supplement group, alkaline phosphate and procollagen type 1, c-terminal show a significant decrease (p=0.001), while the difference was not significant in the control group.conclusion: generally, the research results show that the intensive aerobic exercise and adequate intake of calcium and vitamin d affect positively the bone mass development during youth and they reduce fracture risk; however, such claim needs further investigations.