coagulation disorder’s in sars-cov-2 patients

Context: severe acute respiratory syndrome coronavirus 2 (sars-cov-2) causes coronavirus disease of 2019 (covid-19). pulmonary manifestations have been identified as the common symptom, and patients present a wide range of hematologic changes depending on the flow of the diseases. the interpretation and treatment of hematological complications in covid-19 patients are very challenging. there are limited guidelines thus far due to the novelty of the disease. evidence acquisition: this review summarizes the hematological findings (platelet and coagulation/fibrinolytic) in covid-19 patients and discusses possible mechanisms for their changes. results: the results showed that the common findings were thrombocytopenia, elevated d-dimer levels, and prolonged prothrombin time (pt) and partial thromboplastin time (ptt) in severe patients. conclusions: attention to hematological changes may be helpful biomarkers in diagnosing and determining patients needing intensive care, as well as monitoring the treatment process and treatment effects on covid-19 patients.