the effect of apple juice on antioxidant enzymes and lipid profiles in orchidectomized rats

Background: the age-dependent worsening of lipid profiles increased the risk of cardiovascular disease in males. eating fruits and vegetables is known to be beneficial on lipid profile. objectives: the objective of this research was to delineate whether drinking daily squeezed apple juice (aj) modulates lipid profile and antioxidant enzymes in the animal model that gonadectomized. materials and methods: in this experimental study, 28 male rats were equally divided among the following 4 groups: group i (control), orchidectomized (orx), orx +aj 10%, and orx+ aj 25%. after 60 days of drinking aj, superoxide dismutase (sod), alkaline phosphatase (alp), cholesterol, ldl, hdl and triglycerides in serum were evaluated. data analyzed by spss-16 and computed using one way anova followed by tukey multiple comparison test. p < 0.05 was statistically significant. results: in the orx group compared with the sham group serum sod and alp activities decreased (p < 0.05), while serum cholesterol, triglycerides, ldl increased but hdl decreased in orx groups (p < 0.05). in contrast to the orx group, drinking aj decreased (p < 0.05) concentration of ldl, tg and cholesterol in the serum. aj also increased (p < 0.05) serum hdl, sod and alp activities compared with the orx group. conclusions: drinking aj prevented oxidative stress by elevating serum antioxidant enzymes