frequency of toxoplasma infection among pregnant women and their newborn in kashan, iran

Background: congenital toxoplasmosis (ct) is the result of maternal infection if acquired during gestation, an infection that most often is clinically unapparent. objectives: this study was conducted to determine acute and chronic toxoplamosis in pregnant women and its complications in newborn. patients and methods: in this cohort study, 798 pregnant women were tested for toxoplasma igg/igm by elisa. pcr and igm were performed on 4 newborns of acute and 5 chronic maternal infections; they were followed for 1 year. data were analyzed by spss-11.5 and χ2 test. results: five (0.63%) and 341 (42.7%) were positive for acute and chronic infections. a 400 bp band was seen in 3 newborns of acute maternal infections. the incidence of neonatal toxoplasmosis was 3.7 per 1000. only one neonate of the acute maternal toxoplasmosis had jaundice. conclusions: the rate of maternal and neonatal toxoplasmosis, were higher than the world. jaundice was only sign in newborn with toxoplasma gondii infection.