fabrication of gelatin nano-capsules incorporate ferula assa-foetida essential oil with antibacterial and antioxidant

Background: manufacturing gelatin nano-capsules merged with ferula assa-foetida essential oil, antioxidant and antibacterial properties to produce drugs with properties targeted drug delivery to the body. objectives: in this study, we proved that gelatin nano-capsules grafted with f. assa-foetida essential oil have excellent physical, well as good antioxidant and antibacterial activity, which is suitable for producing nano-capsules of antioxidant antibacterial drug. materials and methods: in this experimental study, gelatinnano-capsules were prepared from gelatin solutions (10% w/v) containing f. assa-foetida essential oil (fao) (2, 4, 6 and 8% w/w), glycerol (25% w/w) as plasticizer and glutaraldehyde (2% w/w) as cross-linker. the morphology, antioxidant and antibacterial properties of the nano-capsules were achieved according to american society for testing and materials. results: gelatin nano-capsules exhibited low antioxidant activity while gelatin nano-capsules incorporated with fao exhibited excellent antioxidant properties. the nano-capsules incorporated with fao also exhibited excellent antibacterial properties against both gram-positive and gram-negative bacteria. conclusions: according to the results, gelatin nano-capsules are good nominations for a variety of antibiotic replacement industrial. the nano-capsules as well as due to the risk of bacterial resistance stay safe. the nano-capsules according to the origin of the whole plant do not have any negative effects on the body.