spreading of extended-spectrum beta-lactamases among the klebsiella pneumoniae strains isolated from outpatients with urinary tract infection in zahedan, southeast iran

Background: extended-spectrum beta-lactamases (esbls) represents a significant and rapid emerging problem around the world. nowadays, antibiotic resistance determinants are prevalent in both hospital and community strains of gram-negative enteric bacteria. materials and methods: in this sectional-descriptive study, 87 clinical isolates of klebsiella pneumoniae were collected from outpatients and their susceptibility to antimicrobial agents, minimum inhibitory concentration (mic) values for third-generation cephalosporins and esbls production were assessed. results: of 87 k. pneumoniae clinical isolates, 20 (22.9%) isolates represented the esbls phenotype. conclusions: our results demonstrated that the resistance to the third-generation cephalosporins in k. pneumoniae strains isolated from outpatients is relatively high in zahedan.