Antibiotic Resistance Pattern of Extended-Spectrum Beta-Lactamases-Producing Klebsiella pneumoniae Clinical Isolates from Zahedan, Southeast Iran

Background: resistance to various classes of antibiotics iscommonamong extended-spectrum beta-lactamases (esbls)-producing bacteria. objectives: to determine the antibiotic resistance pattern of esbls-producing k. pneumoniae clinical isolates from zahedan. methods: in this sectional-descriptive study, susceptibility of 51 esbls-producing k. pneumoniae isolates to 18 antimicrobial agents was determined. results: all isolates were resistant to cefotaxime, cefpodoxime and amoxicillin as well as susceptible to colistin sulfate. also, most isolates were resistant to trimethoprim/sulfamethoxazole and aztreonam. conclusions: our findings demonstrated that the rate of resistance to beta-lactams, sulfonamides, tetracyclines, aminoglycosides and fluoroquinolones in esbls-producing k. pneumoniae isolates is high in zahedan.