>
Fa   |   Ar   |   En
   Immune cells link obesity-associated type 2 diabetes and periodontitis  
   
نویسنده zhu m. ,nikolajczyk b.s.
منبع journal of dental research - 2014 - دوره : 93 - شماره : 4 - صفحه:346 -352
چکیده    The clinical association between obesity-associated type 2 diabetes (t2d) and periodontitis,coupled with the increasing prevalence of these diseases,justifies studies to identify mechanisms responsible for the vicious feed-forward loop between systemic and oral disease. changes in the immune system are critical for both obesity-associated t2d and periodontitis and therefore may link these diseases. recent studies at the intersection of immunology and metabolism have greatly advanced our understanding of the role the immune system plays in the transition between obesity and obesity-associated t2d and have shown that immune cells exhibit similar functional changes in obesity/t2d and periodontitis. furthermore,myeloid and lymphoid cells likely synergize to promote obesity/t2d-associated periodontitis despite complexities introduced by disease interaction. thus the groundwork is being laid for researchers to exploit existing models to understand immune cell dysfunction and break the devastating relationship between obesity-associated t2d and oral disease. © international & american associations for dental research.
کلیدواژه cell biology; cytokine(s); inflammation; periodontal disease
آدرس department of microbiology,boston university,school of medicine,boston,ma, United States, department of microbiology,boston university,school of medicine,boston,ma,united states,department of medicine,boston university,school of medicine,boston,ma, United States
 
     
   
Authors
  
 
 

Copyright 2023
Islamic World Science Citation Center
All Rights Reserved