Clinical trial registration in oral health journals

Prospective registration of randomized controlled trials (rcts) represents the best solution to reporting bias. the extent to which oral health journals have endorsed and complied with rct registration is unknown. we identified journals publishing rcts in dentistry,oral surgery,and medicine in the journal citation reports. we classified journals into 3 groups: journals requiring or recommending trial registration,journals referring indirectly to registration,and journals providing no reference to registration. for the 5 journals with the highest 2012 impact factors in each group,we assessed whether rcts with results published in 2013 had been registered. of 78 journals examined,32 (41%) required or recommended trial registration,19 (24%) referred indirectly to registration,and 27 (35%) provided no reference to registration. we identified 317 rcts with results published in the 15 selected journals in 2013. overall,73 (23%) were registered in a trial registry. among those,91% were registered retrospectively and 32% did not report trial registration in the published article. the proportion of trials registered was not significantly associated with editorial policies: 29% with results in journals that required or recommended registration,15% in those that referred indirectly to registration,and 21% in those providing no reference to registration (p = 0.05). less than one-quarter of rcts with results published in a sample of oral health journals were registered with a public registry. improvements are needed with respect to how journals inform and require their authors to register their trials. © international & american associations for dental research.