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Craniosynostosis and Resynostosis
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نویسنده
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hermann c.d. ,hyzy s.l. ,olivares-navarrete r. ,walker m. ,williams j.k. ,boyan b.d. ,schwartz z.
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منبع
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journal of dental research - 2016 - دوره : 95 - شماره : 8 - صفحه:846 -852
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چکیده
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Craniosynostosis occurs in approximately 1 in 2,000 children and results from the premature fusion of ≥1 cranial sutures. if left untreated,craniosynostosis can cause numerous complications as related to an increase in intracranial pressure or as a direct result from cranial deformities,or both. more than 100 known mutations may cause syndromic craniosynostosis,but the majority of cases are nonsyndromic,occurring as isolated defects. most cases of craniosynostosis require complex cranial vault reconstruction that is associated with a high risk of morbidity. while the first operation typically has few complications,bone rapidly regrows in up to 40% of children who undergo it. this resynostosis typically requires additional surgical intervention,which can be associated with a high incidence of life-threatening complications. this article reviews work related to the dental and maxillofacial implications of craniosynostosis and discusses clinically relevant animal models related to craniosynostosis and resynostosis. in addition,information is provided on the imaging modalities used to study cranial defects in animals and humans. © international & american associations for dental research.
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کلیدواژه
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animal models; maxillofacial; osteogenesis; review; sutures; three-dimensional imaging
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آدرس
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school of medicine,emory university,atlanta,ga, United States, department of biomedical engineering,school of engineering,virginia commonwealth university,601 west main street,richmond,va, United States, department of biomedical engineering,school of engineering,virginia commonwealth university,601 west main street,richmond,va, United States, wallace h. coulter department of biomedical engineering,georgia tech and emory university,georgia institute of technology,atlanta,ga, United States, children's healthcare of atlanta,atlanta,ga, United States, department of biomedical engineering,school of engineering,virginia commonwealth university,601 west main street,richmond,va,united states,wallace h. coulter department of biomedical engineering,georgia tech and emory university,georgia institute of technology,atlanta,ga, United States, department of biomedical engineering,school of engineering,virginia commonwealth university,601 west main street,richmond,va,united states,department of periodontics,university of texas,health science center at san antonio,san antonio,tx, United States
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Authors
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