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A novel mesoporous biomaterial for treating dentin hypersensitivity
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نویسنده
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chiang y.-c. ,chen h.-j. ,liu h.-c. ,kang s.-h. ,lee b.-s. ,lin f.-h. ,lin h.-p. ,lin c.-p.
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منبع
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journal of dental research - 2010 - دوره : 89 - شماره : 3 - صفحه:236 -240
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چکیده
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An ideal material has yet to be discovered that can completely treat dentin hypersensitivity; however,calcium phosphate precipitation has exhibited potential value for the treatment of dentin hypersensitivity by the occlusion of dentinal tubules. we hypothesized that a novel mesoporous silica biomaterial (nano cao@mesoporous silica,ncms) containing nano-sized calcium oxide particles mixed with 30% phosphoric acid can efficiently occlude dentinal tubules and significantly reduce dentin permeability,even with the presence of pulpal pressure. this highly supersaturated ca2+- and hpo4 2-ion-containing ncms paste was brushed onto dentin surfaces,and the ions diffused deeply into the dentinal tubules and formed a cahpo 4·2h2o precipitation with a depth of 100 μm. the results of the dentin permeability tests showed that the novel mesoporous material exhibited a significant reduction in dentin permeability (p < 0.05),even under simulated pulpal pressure,as compared with our previously developed material,dp-bioglass,and a commercial desensitizing material,seal & protect®.
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کلیدواژه
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Bioactive glass; CaO; Dentin hypersensitivity; Dentin permeability; Mesoporous silica
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آدرس
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school of dentistry,graduate institute of clinical dentistry,national taiwan university hospital,no. 1,chang-te street,taipei 10016, Taiwan, school of dentistry,graduate institute of clinical dentistry,national taiwan university hospital,no. 1,chang-te street,taipei 10016, Taiwan, school of dentistry,graduate institute of clinical dentistry,national taiwan university hospital,no. 1,chang-te street,taipei 10016, Taiwan, school of dentistry,graduate institute of clinical dentistry,national taiwan university hospital,no. 1,chang-te street,taipei 10016, Taiwan, school of dentistry,graduate institute of clinical dentistry,national taiwan university hospital,no. 1,chang-te street,taipei 10016, Taiwan, college of medicine,national taiwan university,taipei, Taiwan, department of chemistry,national cheng-kung university,no. 1,university road,tainan 701, Taiwan, school of dentistry,graduate institute of clinical dentistry,national taiwan university hospital,no. 1,chang-te street,taipei 10016, Taiwan
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Authors
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