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ESR detection of ROS generated by TiO2 coated with fluoridated apatite
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نویسنده
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sawada t. ,yoshino f. ,kimoto k. ,takahashi y. ,shibata t. ,hamada n. ,sawada t. ,toyoda m. ,lee m.-c.
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منبع
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journal of dental research - 2010 - دوره : 89 - شماره : 8 - صفحه:848 -853
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چکیده
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Specific materials used in the manufacture of dentures may enhance the removal of micro-organisms. the ultraviolet a (uva) irradiation of acrylic resin containing titanium dioxide (tio2) generates reactive oxygen species (ros) by photocatalysis that shows antibacterial effects. in this study,we tested the hypothesis that tio2 coated with fluoridated apatite (fap-tio2) can generate ros via photocatalysis by using electron spin resonance (esr),and that acrylic resin containing fap-tio2 can show antifungal properties by measuring the viability of candida albicans. we demonstrated that hydroxyl radicals (ho.) were generated through excitation of tio2,tio2 coated with apatite (hap-tio 2),and fap-tio2. the ho. generation through excitation of fap-tio2 was higher than that of tio2 and hap-tio2. regarding antifungal activity,cell viability on acrylic resin containing fap-tio2 was lower than that of tio2 and hap-tio2. faptio2 showed superior photocatalytic effects,and these characteristics may lead to novel methods for the clinical application of denture-cleaning treatments. © international & american associations for dental research.
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کلیدواژه
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acrylic resin; electron spin resonance (ESR); fluoridated apatite (FAp); reactive oxygen species (ROS); titanium dioxide (TiO2)
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آدرس
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division of removal prosthetics,department of oral and maxillofacial rehabilitation,kanagawa dental college,yokosuka,kanagawa, Japan, division of pharmacology and esr laboratories,department of clinical care medicine,kanagawa dental college,82 inaoka-cho,yokosuka,kanagawa,238-8580, Japan, division of fixed prosthodontics,department of oral and maxillofacial rehabilitation,kanagawa dental college,yokosuka,kanagawa, Japan, division of microbiology,department of infection control,kanagawa dental college,yokosuka,kanagawa, Japan, division of fixed prosthodontics,department of oral and maxillofacial rehabilitation,kanagawa dental college,yokosuka,kanagawa, Japan, division of microbiology,department of infection control,kanagawa dental college,yokosuka,kanagawa, Japan, division of removal prosthetics,department of oral and maxillofacial rehabilitation,kanagawa dental college,yokosuka,kanagawa, Japan, division of removal prosthetics,department of oral and maxillofacial rehabilitation,kanagawa dental college,yokosuka,kanagawa, Japan, division of pharmacology and esr laboratories,department of clinical care medicine,kanagawa dental college,82 inaoka-cho,yokosuka,kanagawa,238-8580, Japan
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Authors
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