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Biodegradation of resin-dentin interfaces increases bacterial microleakage
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نویسنده
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kermanshahi s. ,santerre j.p. ,cvitkovitch d.g. ,finer y.
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منبع
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journal of dental research - 2010 - دوره : 89 - شماره : 9 - صفحه:996 -1001
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چکیده
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Bis-gma-containing resin composites and adhesives undergo biodegradation by human-saliva-derived esterases,yielding bis-hydroxy-propoxy-phenylpropane (bis-hppp). the hypothesis of this study is that the exposure of dental restorations to saliva-like esterase activities accelerates marginal bacterial microleakage. resin composites (scotchbond,z250,3m) bonded to human dentin were incubated in either buffer or dual-esterase media (pseudocholinesterase/ cholesterol-esterase; pce+ce),with activity levels simulating those of human saliva,for up to 90 days. incubation solutions were analyzed for bis-hppp by high-performance liquid chromatography. post-incubation,specimens were suspended in a chemostat-based biofilm fermentor cultivating streptococcus mutans ng8,a primary species associated with dental caries,for 7 days. bacterial microleakage was assessed by confocal laser scanning microscopy. bis-hppp production and depth and spatial volume of bacterial cell penetration within the interface increased with incubation time and were higher for 30- and 90-day pce+ce vs. buffer-incubated groups,suggesting that biodegradation can contribute to the formation of recurrent decay. © international & american associations for dental research.
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کلیدواژه
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bacterial microleakage; biodegradation; resin-dentin interface
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آدرس
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biomaterials discipline,dental research institute,university of toronto,124 edward street,toronto,on m5g 1g6, Canada, biomaterials discipline,dental research institute,university of toronto,124 edward street,toronto,on m5g 1g6,canada,department of chemical engineering and applied chemistry,faculty of engineering,university of toronto,on,canada,institute of biomaterials and biomedical engineering,university of toronto,on, Canada, microbiology discipline,faculty of dentistry,university of toronto,on,canada,institute of biomaterials and biomedical engineering,university of toronto,on, Canada, biomaterials discipline,dental research institute,university of toronto,124 edward street,toronto,on m5g 1g6, Canada
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Authors
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