Effects of regular and low-fluoride dentifrices on plaque fluoride

Previous studies have indicated that the use of low-fluoride dentifrices could lead to proportionally higher plaque fluoride levels when compared with conventional dentifrices. this double-blind,randomized,crossover study determined the effects of placebo,low-fluoride,and conventional dentifrices on plaque fluoride concentrations ([f]) in children living in communities with 0.04,0.72,and 3.36 ppm f in the drinking water. children used the toothpastes twice daily,for 1 wk. samples were collected 1 and 12 hrs after the last use of dentifrices and were analyzed for fluoride and calcium. similar increases were found 1 hr after the children brushed with low-fluoride (ca. 1.9 mmol f/kg) and conventional (ca. 2.4 mmol f/kg) dentifrices in the 0.04- and 0.72-ppm-f communities. despite the fact that the increases were less pronounced in the 3.36-ppm-f community,our results indicate that the use of a low-fluoride dentifrice promotes a proportionally higher increase in plaque [f] when compared with that achieved with a conventional dentifrice,based on dose-response considerations. © 2010 international & american associations for dental research.