Efficacy of a tin/fluoride rinse: A randomized in situ trial on erosion

Concentrated tin- and fluoride-containing mouthrinses are effective erosion inhibitors in enamel and dentin. to test whether this is also true for solutions with lower concentrations,we conducted a randomized double-blind three-cell crossover in situ study with extra-orally performed erosive impacts (citric acid,6 × 5 min/day) and an intraoral rinsing protocol (1 × 30 sec/day) in 24 volunteers. the mouthrinses were a placebo,a naf (500 ppm f-),and an amine fluoride (amf)/naf/sncl2 mouthrinse (500 ppm f-,800 ppm sn2+). compared with the placebo,the naf mouthrinse reduced substance loss by 19% in enamel and 23% in dentin (p ≤ 0.01 each); the amf/naf/sncl2 mouthrinse reduced this parameter by 67% in enamel and 47% in dentin (p ≤ 0.001 each). amf/naf/sncl2 was significantly more effective than naf in both tissues (p ≤ 0.01). the mouthrinse containing sn and f exhibited good efficacy,even under severe erosive conditions. © 2010 international & american associations for dental research.