Periodontal disease and incident diabetes: A seven-year study

Diabetes is associated with a high prevalence of periodontal disease,but little is known about the effects of periodontal disease on incident diabetes. in total,5848 non-diabetic individuals aged 30-59 yrs who completed a health examination were analyzed in this study. they were divided into three categories: no pathological pockets,moderate periodontitis,or severe periodontitis. incident diabetes was defined as newly diagnosed cases with fasting plasma glucose > 125 mg/dl. cox proportional hazards models estimated the effect of periodontitis on incident diabetes during a seven-year follow-up period. moderate and severe periodontitis was significantly associated with an increased risk of diabetes in unadjusted analyses,but the magnitude of the association decreased after full adjustment [hazard ratio (hr) = 1.00,95% confidence interval (95% ci) = 0.77-1.30 and hr = 1.28,95% ci = 0.89-1.86,respectively]. our findings do not indicate an apparent association between periodontitis and incident diabetes,although there was a tendency for increased risk. © 2011 international & american associations for dental research.