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Nanofibrous scaffolds for dental and craniofacial applications
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نویسنده
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gupte m.j. ,ma p.x.
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منبع
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journal of dental research - 2012 - دوره : 91 - شماره : 3 - صفحه:227 -234
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چکیده
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Tissue-engineering solutions often harness biomimetic materials to support cells for functional tissue regeneration. three-dimensional scaffolds can create a multi-scale environment capable of facilitating cell adhesion,proliferation,and differentiation. one such multi-scale scaffold incorporates nanofibrous features to mimic the extracellular matrix along with a porous network for the regeneration of a variety of tissues. this review will discuss nanofibrous scaffold synthesis/fabrication,biological effects of nanofibers,their tissue- engineering applications in bone,cartilage,enamel,dentin,and periodontium,patient-specific scaffolds,and incorporated growth factor delivery systems. nanofibrous scaffolds cannot only further the field of craniofacial regeneration but also advance technology for tissue-engineered replacements in many physiological systems. © 2012 international & american associations for dental research.
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کلیدواژه
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biomaterials; craniofacial; drug delivery; Nanofibrous scaffold; stem cell; tissue engineering
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آدرس
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department of biomedical engineering,1011 north university ave.,ann arbor,mi 48109-1078, United States, department of biomedical engineering,1011 north university ave.,ann arbor,mi 48109-1078,united states,department of biologic and materials sciences,1011 north university ave.,ann arbor,mi 48109-1078,united states,macromolecular science and engineering center,university of michigan,ann arbor,mi 48109-1078,united states,department of materials science and engineering,university of michigan,ann arbor,mi 48109-1078, United States
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Authors
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