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The sensitivity of the human chromosomes to ethyl methane sulfonate (EMS) [Etil metansulfonat (EMS)'ye i̇nsan kromozomlari{dotless}ni{dotless}n hassasiyeti]
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نویسنده
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budak diler s. ,topaktaş m.
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منبع
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journal of cell and molecular biology - 2010 - دوره : 7-8 - شماره : 2-1 - صفحه:25 -34
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چکیده
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The aim of this study was to determine the chromosomal susceptibility to breakages by the mutagen ethyl methanesulfonate (ems). for this reason,human peripheral blood lymphocytes were treated with varying concentrations of ems (5×10-4m,10-3m and 2×10-3m) for 24 and 48 hours. the percentages of chromosomal fragmentations in ems-treated and untreated (control) cells were found to be statistically significant. in addition,the extent of breakages of the same chromosomes correlated with the concentrations of the chemical. the chromosomes that were fragmented most as a result of ems-treatment in descending order were 1,2,6,4,x,7,3,5,9,and 8.
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کلیدواژه
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Chromosome damage; Ethyl methanesulfonate (EMS); Human lymphocytes; Lymphocyte culture
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آدرس
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university of niǧde,department of science and letters,niǧde, Turkey, university of cukurova,department of science and letters, Turkey
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Authors
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