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Vascular and plaque imaging with ultrasmall superparamagnetic particles of iron oxide
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نویسنده
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alam s.r. ,stirrat c. ,richards j. ,mirsadraee s. ,semple s.i.k. ,tse g. ,henriksen p. ,newby d.e.
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منبع
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journal of cardiovascular magnetic resonance - 2015 - دوره : 17 - شماره : 1
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چکیده
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Cardiovascular magnetic resonance (cmr) has become a primary tool for non-invasive assessment of cardiovascular anatomy,pathology and function. existing contrast agents have been utilised for the identification of infarction,fibrosis,perfusion deficits and for angiography. novel ultrasmall superparamagnetic particles of iron oxide (uspio) contrast agents that are taken up by inflammatory cells can detect cellular inflammation non-invasively using cmr,potentially aiding the diagnosis of inflammatory medical conditions,guiding their treatment and giving insight into their pathophysiology. in this review we describe the utilization of uspio as a novel contrast agent in vascular disease. © 2015 alam et al.
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کلیدواژه
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Cardiovascular imaging; CMR; Inflammation; Macrophage; Nanoparticles; USPIO
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آدرس
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centre for cardiovascular science,university of edinburgh,chancellor's building,little france crescent,edinburgh,eh16 5sa,united kingdom,department of cardiology,royal infirmary of edinburgh,edinburgh,eh16 5sa, United Kingdom, centre for cardiovascular science,university of edinburgh,chancellor's building,little france crescent,edinburgh,eh16 5sa,united kingdom,department of cardiology,royal infirmary of edinburgh,edinburgh,eh16 5sa, United Kingdom, centre for cardiovascular science,university of edinburgh,chancellor's building,little france crescent,edinburgh,eh16 5sa, United Kingdom, clinical research imaging centre,university of edinburgh,edinburgh,eh16 5sa,united kingdom,department of radiology,royal infirmary of edinburgh,edinburgh,eh16 5sa, United Kingdom, clinical research imaging centre,university of edinburgh,edinburgh,eh16 5sa, United Kingdom, mrc centre for inflammation research,university of edinburgh,edinburgh,eh16 5sa, United Kingdom, centre for cardiovascular science,university of edinburgh,chancellor's building,little france crescent,edinburgh,eh16 5sa,united kingdom,department of cardiology,royal infirmary of edinburgh,edinburgh,eh16 5sa, United Kingdom, centre for cardiovascular science,university of edinburgh,chancellor's building,little france crescent,edinburgh,eh16 5sa,united kingdom,department of cardiology,royal infirmary of edinburgh,edinburgh,eh16 5sa, United Kingdom
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Authors
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