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The association between the cardio-ankle vascular index and other parameters of vascular structure and function in Caucasian adults: MARK study
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نویسنده
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gomez-sanchez l. ,garcia-ortiz l. ,patino-alonso m.c. ,recio-rodriguez j.i. ,frontera g. ,ramos r. ,martí r. ,agudo-conde c. ,rodriguez-sanchez e. ,maderuelo-fernández j.a. ,gomez-marcos m.a.
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منبع
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journal of atherosclerosis and thrombosis - 2015 - دوره : 22 - شماره : 9 - صفحه:901 -911
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چکیده
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Aim: we assessed whether there is an association between the cardio-ankle vascular index (cavi) score and the carotid intima media thickness (imt),the pulse wave velocity (pwv) and the central augmentation index (caix) that is independent of the subject’s cardiovascular risk and pharmacological treatment. methods: the cavi score was measured in 500 subjects using a vasera device and the brachial ankle pwv (ba-pwv) was calculated. a carotid ultrasound was used to measure the imt. a mobil-ograph device was used to measure the carotid femoral pwv (cf-pwv) and the caix. the framingham-d’agostino and score scales were used to measure the subject’s cardiovascular risk. results: the mean value of the cavi score was 8.59±1.1. imt,caix and pwv maintai ned a positive association with the cavi score (p<0.01) in a multiple linear regression analysis,after adjusting for the subject’s cardiovascular risk,body mass index and pharmacological treatment. the cut-off level that gave the maxima sensitivity and specificity to detect a mean imt of >0.90 mm was 8.95 (auc=0.67) for the cavi score,8.85 (auc=0.66) for cf-pwv and 15.10 (auc=0.66) for ba-pwv. the cut-off to detect a maxima imt of >0.90 mm was 8.60 (auc=0.62) for the cavi score,8.85 (auc=0.64) for cf-pwv and 15.75 (auc=0.70) for ba-pwv. conclusion: there was a positive association of the cavi score with vascular structure and function parameters that was independent of cardiovascular risk and any medications being used by the subject. the ability of the cavi score to predict carotid atherosclerosis is similar to that of cf-pwv and ba-pwv in caucasian adults. © 2015,japan atherosclerosis society. all rights reserved.
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کلیدواژه
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Cardio-ankle vascular index (CAVI); Cardiovascular risk; Vascular function; Vascular structure
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آدرس
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primary care research unit,the alamedilla health center,salamanca, Spain, primary care research unit,the alamedilla health center,salamanca,spain,castilla and león health service–sacyl salamanca,salamanca,spain,medicine department,university of salamanca,salamanca, Spain, primary care research unit,the alamedilla health center,salamanca,spain,statistics department,university of salamanca,salamanca, Spain, primary care research unit,the alamedilla health center,salamanca,spain,castilla and león health service–sacyl salamanca,salamanca, Spain, cs g. corsaib,primare care ibsalut,palma of mallorca, Spain, research unit,family medicine,girona. jordi gol institute for primary care research (idiap jordi gol),girona,spain,trans research group,department of medical sciences,school of medicine,university of girona,girona,spain,girona biomedical research institute (idibgi),dr. trueta university hospital,catalonia, Spain, research unit,family medicine,girona. jordi gol institute for primary care research (idiap jordi gol),girona,spain,girona biomedical research institute (idibgi),dr. trueta university hospital,catalonia, Spain, primary care research unit,the alamedilla health center,salamanca,spain,castilla and león health service–sacyl salamanca,salamanca, Spain, primary care research unit,the alamedilla health center,salamanca,spain,castilla and león health service–sacyl salamanca,salamanca,spain,medicine department,university of salamanca,salamanca, Spain, primary care research unit,the alamedilla health center,salamanca,spain,castilla and león health service–sacyl salamanca,salamanca, Spain, primary care research unit,the alamedilla health center,salamanca,spain,castilla and león health service–sacyl salamanca,salamanca,spain,medicine department,university of salamanca,salamanca, Spain
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Authors
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