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   Application of new guidelines for the primary prevention of atherosclerotic cardiovascular disease in a Korean population  
   
نویسنده kim n.h. ,so m.-s. ,kang j.-g. ,cho d.-s. ,byrne c.d. ,lee s.j. ,sung k.-c.
منبع journal of atherosclerosis and thrombosis - 2015 - دوره : 22 - شماره : 3 - صفحه:293 -303
چکیده    Aim: we investigated the proportion of people who would qualify for statin treatment with an atherosclerotic cardiovascular disease (ascvd) 10-year risk of ≥7.5% and who exhibit an ldl cholesterol (ldl-c) of 70 to 189 mg/dl according to the new acc/aha guidelines for the treatment of increased cardiovascular risk. methods: the study population (8,742 subjects) included individuals who underwent health examinations at kangbuk samsung hospital in south korea in 2010. we also evaluated the data obtained from the 2008-2010 korea national health and nutrition examination survey (knhanes) of 16,892 adults. results: approximately 90% of men ≥60 years of age and women ≥70 years of age had an ascvd 10-year risk of ≥7.5% and ldl-c level of ≥70 mg/dl. the proportions of subjects with a framingham 10-year risk of ≥10%,coronary artery calcium score of >20 and >100 and fatty liver each increased in association with an increasing ascvd 10-year risk quartile in both sexes. furthermore,age was significantly associated with the ascvd 10-year risk in both sexes (all p-value <0.001). the knhanes data also showed that over 85.0% of men ≥60 years of age and 95.0% of women ≥70 years of age had an ascvd 10-year risk of ≥7.5% and an ldl-c level of ≥70 mg/dl. conclusions: adopting the new ascvd prevention guidelines would result in the treatment of almost all korean men and women (≥60 years and ≥70 years of age,respectively) without evidence of cardiovascular disease. therefore,asian-specific guidelines are needed to avoid unnecessary over treatment in an aging global population. © 2015 japan atherosclerosis society.
کلیدواژه Coronary artery calcium; Guidelines; Risk factor; Statin
آدرس department of internal medicine,gangnam cha medical center,cha university,school of medicine,seoul, South Korea, division of cardiology,department of internal medicine,kangbuk samsung hospital,sungkyunkwan university school of medicine,seoul, South Korea, division of cardiology,department of internal medicine,kangbuk samsung hospital,sungkyunkwan university school of medicine,seoul, South Korea, department of internal medicine,eunpyeong teun teun hospital,seoul, South Korea, nutrition and metabolism unit,southampton general hospital,(university of southampton),southampton national institute for health research biomedical research centre,ids building,southampton, United Kingdom, department of internal medicine,gangnam cha medical center,cha university,school of medicine,seoul, South Korea, division of cardiology,department of internal medicine,kangbuk samsung hospital,sungkyunkwan university school of medicine,seoul, South Korea
 
     
   
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