Coronary artery calcium score compared with cardio-ankle vascular index in the prediction of cardiovascular events in asymptomatic patients with type 2 diabetes

Aim: coronary artery calcium (cac score has a role in stratifying cardiovascular risk in patients with diabetes. cardio-ankle vascular index (cavi is also a useful method to detect coronary artery calcification. this study compares cac score with cavi in the prediction of cardiovascular events in patients with diabetes. methods: from august 2006 to june 2008,a total of 626 patients with diabetes who received cac score assessment with concomitant tests of ankle-brachial index and cavi were included in this study. results: during 4 years of follow-up,98 participants developed cardiovascular events. there is an increased incidence of coronary revascularization and total cardiovascular events with higher categories of cac score (p ＜0.05 when cac score ≥100. the logistic regression analyses revealed pooled odd ratios for coronary revascularization,and total cardiovascular events were 1.25 [95% confidence interval (ci 1.03– 1.51,p =0.021] and 1.23 (95% ci 1.07–1.42,p = 0.005,respectively,for high versus low cavi (cavi ≥9.0 vs cavi ＜9.0. the logistic regression model revealed that a cac score of ≥1000 rather than a cavi of ≥9.0 had a higher predictive value for total cardiovascular events. conclusions: a cac score of ≥100 or a cavi of ≥9.0 predicts future total cardiovascular events in asymptomatic patients with type 2 diabetes. considering the advantages of cavi,it can be used as one of the screening tools to reflect coronary atherosclerosis in these patients. © 2015,japan atherosclerosis society. all rights reserved.