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   Body mass index modifies an association between self-reported regular exercise and proteinuria a nationwide cross-sectional survey in Japan  
   
نویسنده nagasawa y. ,yamamoto r. ,shinzawa m. ,hasuike y. ,kuragano t. ,isaka y. ,nakanishi t. ,iseki k. ,yamagata k. ,tsuruya k. ,yoshida h. ,fujimoto s. ,asahi k. ,moriyama t. ,watanabe t.
منبع journal of atherosclerosis and thrombosis - 2016 - دوره : 23 - شماره : 4 - صفحه:402 -412
چکیده    Aim: regular exercise habits are well-known to exert a favorable effect on the metabolic syndrome,which may cause proteinuria and chronic kidney disease (ckd). however,it remains unknown if exercise exerts a favorable effect on proteinuria and kidney dysfunction. the aim of this study was to reveal the association between exercise and the prevalence of proteinuria and kidney dysfunction and the attenuation by obesity. methods: this study was a cross-sectional cohort study that included 292,013 participants who underwent the specific health check and guidance in japan. the exercise score (range 0-3) was based on the number of positive answers to three questions regarding exercise habits. the outcome was defined as urinary protein detected by a dipstick test and kidney dysfunction [estimated glomerular filtration rate (gfr) less than 45 ml/min/1.73 m2]. results: the exercise score was significantly associated with the prevalence of proteinuria in both males [vs. exercise score 0; exercise score 1,multivariate-adjusted odds ratio 0.86 (95% confidence interval 0.81-0.92),p<0.001; exercise score 2,0.84 (0.79-0.90),p<0.001; exercise score 3,0.77 (0.72-0.82),p<0.001] and females (same as in males). after the male subjects were divided into quintiles according to body mass index (bmi) in more than three groups (22.9
کلیدواژه BMI; CKD; Exercise; Proteinuria
آدرس department of internal medicine,division of kidney and dialysis,hyogo college of medicine,hyogo, Japan, osaka university health care center,osaka,japan,department of geriatric medicine and nephrology,osaka university graduate school of medicine,osaka, Japan, department of geriatric medicine and nephrology,osaka university graduate school of medicine,osaka, Japan, department of internal medicine,division of kidney and dialysis,hyogo college of medicine,hyogo, Japan, department of internal medicine,division of kidney and dialysis,hyogo college of medicine,hyogo, Japan, department of geriatric medicine and nephrology,osaka university graduate school of medicine,osaka, Japan, department of internal medicine,division of kidney and dialysis,hyogo college of medicine,hyogo, Japan, steering committee for the ‘research on the positioning of chronic kidney disease in specific health check and guidance in japan’,tokyo, Japan, steering committee for the ‘research on the positioning of chronic kidney disease in specific health check and guidance in japan’,tokyo, Japan, steering committee for the ‘research on the positioning of chronic kidney disease in specific health check and guidance in japan’,tokyo, Japan, steering committee for the ‘research on the positioning of chronic kidney disease in specific health check and guidance in japan’,tokyo, Japan, steering committee for the ‘research on the positioning of chronic kidney disease in specific health check and guidance in japan’,tokyo, Japan, steering committee for the ‘research on the positioning of chronic kidney disease in specific health check and guidance in japan’,tokyo, Japan, osaka university health care center,osaka,japan,department of geriatric medicine and nephrology,osaka university graduate school of medicine,osaka,japan,steering committee for the ‘research on the positioning of chronic kidney disease in specific health check and guidance in japan’,tokyo, Japan, steering committee for the ‘research on the positioning of chronic kidney disease in specific health check and guidance in japan’,tokyo, Japan
 
     
   
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