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Long noncoding RNAs in atherosclerosis
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نویسنده
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jian l. ,jian d. ,chen q. ,zhang l.
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منبع
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journal of atherosclerosis and thrombosis - 2016 - دوره : 23 - شماره : 4 - صفحه:376 -384
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چکیده
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Long noncoding rnas (lncrnas) were a group of non-protein-coding rnas ＞200 nucleotides and participated in biological processes and pathophysiological conditions in vivo or in vitro. recently,more and more lncrnas interfering with the progress of atherosclerosis were identified and characterized in the atherogenic cells such as vascular smooth muscle cells (vsmcs),endothelial cells (ecs),and monocytes/macrophages showing that lncrnas play an important role in the occurrence of atherosclerosis. in this review,we summarized and highlighted the lncrnas that play a role in the process of atherosclerosis. this study may provide helpful insights regarding further study of lncrnas associated with atherosclerosis. © 2016,journal of atherosclerosis and thrombosis. all rights reserved.
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کلیدواژه
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Atherosclerosis; ECs; Long noncoding RNA; Monocyte/macrophages; VSMCs
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آدرس
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department of cardiology,the second affiliated hospital of zhengzhou universityhenan, China, department of cardiology,first affiliated hospital,school of medicine,zhejiang universityzhejiang, China, department of cardiology,first affiliated hospital,school of medicine,zhejiang universityzhejiang, China, department of cardiology,first affiliated hospital,school of medicine,zhejiang universityzhejiang, China
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Authors
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