Twelve-week jogging training increases pre-heparin serum lipoprotein lipase concentrations in overweight/obese middle-aged men

Aim: enhancement of lipoprotein lipase (lpl) activity through drug administration has been shown to increase pre-heparin serum lpl concentrations; however,pre-heparin serum lpl responses to exercise training have not been determined. the present study was undertaken to investigate the effects of 12 weeks of supervised aerobic exercise training on pre-heparin serum lpl concentrations in overweight/obese men. methods: fifteen overweight/obese middle-aged men were assigned to one of two 12-week supervised exercise interventions: a walking group (eight participants gradually increasing brisk walking to 60 min/day 3 days a week) or a jogging group (seven participants gradually increasing jogging to 60 min/day 3 days a week). all participants maintained ad libitum diets. blood samples were collected at baseline and immediately after 12 weeks. the primary outcome was pre-heparin serum lpl. results: pre-heparin serum lpl concentrations were increased in the jogging group after 12 weeks compared with the baseline values (mean±sem: 37.6±4.7 vs. 51.0±6.6 ng/ml,respectively,p=0.033). in the walking group,pre-heparin serum lpl concentrations remained unchanged after 12 weeks. conclusions: this study demonstrates that 12 weeks of jogging training increases pre-heparin serum lpl concentrations in overweight/obese middle-aged men.