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   Changes in weight,cardiovascular risk factors and estimated risk of coronary heart disease following smoking cessation in Japanese male workers: HIPOP-OHP study  
   
نویسنده tamura u. ,tanaka t. ,okamura t. ,kadowaki t. ,yamato h. ,tanaka h. ,nakamura m. ,okayama a. ,ueshima h. ,yamagata z.
منبع journal of atherosclerosis and thrombosis - 2010 - دوره : 17 - شماره : 1 - صفحه:12 -20
چکیده    Aim: it is well established that people gain weight after smoking cessation; however,changes in cardiovascular risk factors and the estimated risk of coronary heart disease following smoking cessation have yet to be fully clarified. methods: the participants were 1,995 japanese male workers at 11 workplaces who participated continuously in the high-risk and population strategy for occupational health promotion (hipopohp) study. participants with a smoking habit had cardiovascular risk factors measured at baseline and over a 4-yr period. their estimated incidence risk of coronary heart disease was calculated by a formula based on a previous cohort study. results: successful abstainers who had stopped smoking for at least 6 months at the end of the follow-up period had weight gains of approximately 2 kg. these subjects had significant worsening of the following factors compared to continuing smokers: systolic and diastolic blood pressure,total cholesterol,triglyceride and fasting blood sugar levels. in contrast,hdl-cholesterol levels improved significantly. when the overall instantaneous incidence risk of coronary heart disease prior to smoking cessation was assumed to be 1.00,the estimated risk was 0.76 (95%ci: 0.68-0.85) in successful abstainers due mainly to smoking cessation,despite weight gain. conclusion: although smoking cessation leads to weight gain,the estimated risk of coronary heart disease was decreased markedly by smoking cessation.
کلیدواژه Blood pressure; Cardiovascular disease; Cholesterol; Lifestyle modification; Smoking cessation
آدرس department of health sciences,school of medicine,university of yamanashi,1110,shimokato,chuo,yamanashi,409-3898, Japan, department of health sciences,school of medicine,university of yamanashi,1110,shimokato,chuo,yamanashi,409-3898, Japan, department of preventive cardiology,national cardiovascular center,suita, Japan, department of health science,shiga university of medical science,otsu, Japan, department of health development,institute of industrial ecological sciences,university of occupational and environmental health,kitakyushu, Japan, division of epidemiology and prevention,aichi cancer center hospital and research institute,nagoya, Japan, department of health promotion and education,osaka medical center for health science and promotion,osaka, Japan, research institute of tuberculosis,japan anti-tuberculosis association,tokyo, Japan, department of health science,shiga university of medical science,otsu, Japan, department of health sciences,school of medicine,university of yamanashi,1110,shimokato,chuo,yamanashi,409-3898, Japan
 
     
   
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