>
Fa   |   Ar   |   En
   Chronic kidney disease,all-cause mortality and cardiovascular mortality among chinese patients with established cardiovascular disease  
   
نویسنده yang j.-g. ,li j. ,lu c. ,hasimu b. ,yang y. ,hu d.
منبع journal of atherosclerosis and thrombosis - 2010 - دوره : 17 - شماره : 4 - صفحه:395 -401
چکیده    Aim: this study was conducted to investigate the role of chronic kidney disease (ckd) in 1-year allcause mortality and cardiovascular mortality among chinese patients who were at least 50 years old and had a history of coronary artery disease (cad),stroke,or peripheral vascular disease (pad),or with two or more cardiovascular risks. methods: of 3,732 hospitalized patients enrolled,3,423 patients (91.7%) with complete data were eligible for 1-year follow-up. ckd was defined as an estimated glomerular filtration rate (egfr) of < 60 ml/min/1.73 m2. results: 1,166 (34.1%) were diagnosed with ckd. most cases were unrecognized. patients having an egfr of <30 ml/min/1.73 m2 were less likely to be prescribed beta-blockers,statins,or aspirin (all p<0.001). a powerful relationship was observed between the severity of renal dysfunction and all causes of death or cardiovascular death. adjusted for other covariates,the hazard ratio (hr) for all causes of death and for cardiovascular death among patients with an egfr of < 30 ml/min/1.73 m2 was 1.70 (95% ci,1.18 - 2.45) and 1.85 (95% ci,1.12 - 3.01) as compared with 2.93 (95% ci,1.96 - 4.38) and 3.47 (95% ci,1.91 -6.31) for patients with an egfr of 7lt;30 ml/min/1.73 m2. conclusions: one third of chinese patients at high risk for atherosclerotic events were diagnosed with ckd. most of these cases were unrecognized and undertreated. an egfr of <45 ml/min/1.73 m2 was an independent predictor of all causes of death and of cardiovascular death.
کلیدواژه All-cause mortality; Cardiovascular disease; Cardiovascular mortality; Chronic kidney disease
آدرس cardiovascular institute and fuwai hospital,chinese academy of medical sciences and peking union medical college,beijing, China, heart,lung and blood vessel center,tongji university,shanghai, China, cardiovascular center,beijing tongren hospital,beijing medical university,beijing, China, heart center,first teaching hospital of xinjiang medical university,urumqi, China, cardiovascular institute and fuwai hospital,chinese academy of medical sciences and peking union medical college,beijing, China, heart center,people's hospital of peking university,beijing 100044, China
 
     
   
Authors
  
 
 

Copyright 2023
Islamic World Science Citation Center
All Rights Reserved