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   Relationship of the polyunsaturated to saturated fatty acid ratio to cardiovascular risk factors and metabolic syndrome in japanese: the INTERLIPID study  
   
نویسنده guo z. ,miura k. ,turin t.c. ,hozawa a. ,okuda n. ,okamura t. ,saitoh s. ,sakata k. ,nakagawa h. ,okayama a. ,yoshita k. ,kadowaki t. ,choudhury s.r. ,nakamura y. ,rodriguez b.l. ,curb j.d. ,elliott p. ,stamler j. ,ueshima d.h.
منبع journal of atherosclerosis and thrombosis - 2010 - دوره : 17 - شماره : 8 - صفحه:777 -784
چکیده    Aim: there have been few studies on the relationships of the dietary polyunsaturated to saturated fatty acid ratio (p/s) to cardiovascular risk factors and metabolic syndrome. we hypothesized that there would be favorable relationships. & methods: metabolic cardiovascular risk factors from dietary nutrient intake were investigated in 1,004 men and women aged 40-59 years from 4 population samples of japanese. multiple linear regression analysis was used to examine the relationship of the dietary p/s ratio to the following risk factors: hemoglobin a1c,blood pressure,serum triglycerides,ldl and total cholesterol,and hdl-cholesterol. adjusted odds ratio of having metabolic syndrome was also calculated. & results: the dietary p/s ratio was significantly and inversely related to serum total and ldl cholesterol with control for possible confounding variables. we did not find any significant relationship between the p/s ratio and single metabolic risk factors or the prevalence of metabolic syndrome. & conclusions: managing the p/s ratio is important to control serum ldl-cholesterol; however,increasing the p/s ratio may not improve metabolic risk factors. other countermeasures,such as weight control,greater physical activity,and smoking cessation should be recommended to prevent and control metabolic syndrome.
کلیدواژه Japanese; Metabolic syndrome; P/s ratio; Polyunsaturated fatyy acid; Saturated fatty acid
آدرس department of health science,shiga university of medical science,otsu, Japan, department of health science,shiga university of medical science,otsu, Japan, department of health science,shiga university of medical science,otsu, Japan, department of public health and forensic medicine,tohoku university school of medicine,sendai, Japan, department of health science,shiga university of medical science,otsu, Japan, national cardiovascular center,osaka, Japan, department of internal medicine,sapporo medical university,sapporo, Japan, department of hygiene and preventive medicine,iwate medical university school of medicine,morioka, Japan, department of epidemiology and public health,kanazawa medical univerisy,ishikawa, Japan, the research institute of tuberculosis,japan anti-tuberculosis association,tokyo, Japan, national institute of health and nutrition,tokyo, Japan, department of health science,shiga university of medical science,otsu, Japan, department of noncommunicable diseases and mental health,who,dhaka, Bangladesh, kyoto women's university,kyoto, Japan, john a. burns school of medicine,university of hawaii,honolulu,hawaii, United States, john a. burns school of medicine,university of hawaii,honolulu,hawaii, United States, department of epidemiology and public health,faculty of medicine,st mary's campus,imperial college,london, United Kingdom, department of preventive medicine,feinberg school of medicine,northwestern university,chicago, United States, department of health science,shiga university of medical science,otsu, Japan
 
     
   
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