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   Associations of lower-body fat mass with favorable profile of lipoproteins and adipokines in healthy,slim women in early adulthood  
   
نویسنده tanaka s. ,bin w. ,honda m. ,suzuki k. ,yoshino g. ,fukuo k. ,kazumi t.
منبع journal of atherosclerosis and thrombosis - 2011 - دوره : 18 - شماره : 5 - صفحه:365 -372
چکیده    Aim: we determined the association of lower-body fat mass (lfm) and trunk fat mass (tfm) with cardiometabolic risk factors and adipokines in young,healthy,slim women. methods: a total of 481 college female students underwent the following: regional body fat distribution as assessed by dual energy x-ray absorptiometry (dxa),a 75g oral glucose tolerance test (ogtt) and fasting blood sampling for measurement of lipids,lipoproteins,apolipoproteins (apo),liver enzymes and adipokines. results: after adjusting for tfm,lfm was positively associated with hdl cholesterol,adiponectin,pre-heparin lipoprotein lipase and insulin sensitivity,as estimated by the matsuda index,whereas it was negatively related to triglycerides,apo b,apo b/a1 ratio,small dense ldl,ffa,glucose and insulin at 2h during ogtt,area under the curve of insulin response during ogtt and the white blood cell count. participants were divided into 9 groups according to tertiles of tfm and lfm. in the middle tertile of tfm,hdl cholesterol and adiponectin increased and triglycerides,apob/a1 ratio and plasminogen-activator inhibitor-1 decreased from the low to high lfm tertiles. gamma-glutamyltransferase levels in middle and high lfm tertiles were lower than in the lower lfm tertile. conclusion: for a given level of trunk fat mass,a higher lower-body fat mass is associated with an advantageous profile of not only blood lipoproteins but also serum adipokines,even in healthy,slim women in early adulthood.
کلیدواژه Adiponectin; HDL; Lower-body fat; Triglyceride; Trunk fat
آدرس department of food sciences and nutrition,school of human environmental science,mukogawa women's university,hyogo, Japan, open research center for studying of lifestyle-related diseases,mukogawa women's university,hyogo, Japan, open research center for studying of lifestyle-related diseases,mukogawa women's university,hyogo, Japan, department of food sciences and nutrition,school of human environmental science,mukogawa women's university,hyogo,japan,open research center for studying of lifestyle-related diseases,mukogawa women's university,hyogo, Japan, department of diabetes and endocrinology,toho university omori medical center,tokyo, Japan, department of food sciences and nutrition,school of human environmental science,mukogawa women's university,hyogo,japan,open research center for studying of lifestyle-related diseases,mukogawa women's university,hyogo, Japan, department of food sciences and nutrition,school of human environmental science,mukogawa women's university,hyogo,japan,open research center for studying of lifestyle-related diseases,mukogawa women's university,hyogo, Japan
 
     
   
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