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   Antioxidant and hepatic protective effects of lotus root hot water extract with taurine supplementation in rats fed a high fat diet  
   
نویسنده du h. ,zhao x. ,you j.-s. ,park j.-y. ,kim s.-h. ,chang k.-j.
منبع journal of biomedical science - 2010 - دوره : 17 - شماره : SUPPL. 1
چکیده    Background. nelumbo nucifera,known as sacred lotus,is a well-known medicinal plant and this lotus root is commonly used as food compared to different parts of this plant. this study was conducted to investigate the antioxidant and hepatic protective effects of lotus root hot water extract with taurine supplementation in high fat diet-induced obese rats. methods. thirty-two male sprague-dawley rats (4-week-old) were randomly divided into four groups (n=8) for 6 weeks (normal diet,n group; high fat diet,hf group; high fat diet + lotus root hot water extract,hfr group; high fat diet + lotus root hot water extract + taurine,hfrt group). lotus root hot water extract was orally administrated (400mg/kg/day) to hfr and hfrt groups and the same amount of distilled water was orally administered to n and hf groups. taurine was supplemented by dissolving in feed water (3% w/v). results. the activities of glutamate oxaloacetate transaminase and glutamate pyruvate transaminase in serum were lower in hfr and hfrt groups compared to hf group. thiobarbituric acid reactive substance contents in all groups fed a high fat diet were higher compared to n group. the activities of hepatic antioxidant enzymes were higher in hfr and hfrt groups compared to hf group. conclusions. these results suggest that lotus root hot water extract with taurine supplementation shows antioxidant and hepatic protective effects in high fat diet-induced obese rats. © 2010 chang et al; licensee biomed central ltd.
آدرس department of food and nutrition,inha university,incheon, South Korea, department of food and nutrition,inha university,incheon, South Korea, department of food and nutrition,inha university,incheon, South Korea, department of food and nutrition,inha university,incheon, South Korea, department of chemistry,konkuk university,seoul, South Korea, department of food and nutrition,inha university,incheon, South Korea
 
     
   
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