Role of Melatonin and/or Vitamin B Complex against Hormonal Changes in Epinephrine-Stressed Rats

The current study aimed to investigate the effect of intramuscular injection of melatonin (mt)(1mg/ kg) and/or vitamin bcomplex (tri-b) (20 mg/kg) on the hormonal changes induced by epinephrine (epi) (0.02 mg/kg) in male albino rats. intramuscular administration of epi induced significant elevations in adrenocorticotropic hormone (acth), corticosterone (cort), triiodothyronine (t3 ) and thyroxine (t4) 1 evels after the two experimental durations. on the other hand, luetinizing hormone (lh), testosterone , prolactin (prl) and growth hormone (gh) levels were decreased under the same conditions. melatonin treatment seems to constitute a selection therapy, by improving atch, cort, t3 ,t4 and gh levels but has no effect on the low levels of lh , testosterone and prl. also, the data suggested that tri-b injection partially improved the different endocrinological changes of epi