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In vitro adherence of Candida albicans isolated from patients with chronic periodontitis
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نویسنده
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machado a.g. ,komiyama e.y. ,dos santos s.s.f. ,jorge a.o.c. ,brighenti f.l. ,koga-ito c.y.
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منبع
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journal of applied oral science - 2011 - دوره : 19 - شماره : 4
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چکیده
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Adherence is considered an extremely important virulence factor in yeast. objective: the aim of this study was to analyze the adherence to epithelial cells of c. albicans isolated from patients with chronic periodontitis in comparison to healthy patients. material and methods: candida albicans cells isolated from individuals with chronic periodontitis (n = 25) and healthy controls (n=25) were included in this study. suspensions of c. albicans (106 cells/ml) and epithelial cells (105 cells/ml) were mixed and incubated at 37°c for 1 h. the number of yeasts adhered to 25 epithelial cells was counted. results: the number of c. albicans cells adhered to epithelial cells was statistically higher in the chronic periodontitis group than in the control group (student's t-test,p=0.000). conclusion: the results of the present study suggest a higher candida adherence of samples isolated from patients with chronic periodontitis.
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کلیدواژه
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Candida albicans; Cell adhesion; Periodontitis; Virulence factors
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آدرس
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department of biosciences and oral diagnosis,são josé dos campos dental school,state university of são paulo-unesp,av: eng. josé francisco longo,777,12245-000 são josé dos campos,sp, Brazil, department of biosciences and oral diagnosis,são josé dos campos dental school,state university of são paulo-unesp,av: eng. josé francisco longo,777,12245-000 são josé dos campos,sp, Brazil, department of dentistry,university of taubaté (unitau),taubaté,sp, Brazil, department of biosciences and oral diagnosis,são josé dos campos dental school,state university of são paulo-unesp,av: eng. josé francisco longo,777,12245-000 são josé dos campos,sp, Brazil, department of biosciences and oral diagnosis,são josé dos campos dental school,state university of são paulo-unesp,av: eng. josé francisco longo,777,12245-000 são josé dos campos,sp, Brazil, department of biosciences and oral diagnosis,são josé dos campos dental school,state university of são paulo-unesp,av: eng. josé francisco longo,777,12245-000 são josé dos campos,sp, Brazil
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Authors
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