Editorial:In vitro Human Embryo Culture; When Questions Outweigh Answers

More than five million babies have been born by the application of assisted conception methods throughout the world, and about 1% to 2% of babies in developed countries are born by the help of assisted reproductive techniques (art) in couples with infertility. in spite of huge developments in equipments, techniques, procedures, supplies and greater control of environmental factors which affect assisted conception processes, there is mounting concern regarding anomalies and birth defects from assisted conception in the community and, especially, among infertile couples. although this concern is very low compared to the time of application of ivf technology three decades ago, but results of more comprehensive longitudinal studies have revealed increased risk of congenital anomalies, malformation and early pregnancy loss associated with art(1).