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severe immune thrombocytopenic purpura in a patient at 33 weeks of gestation: a case report
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نویسنده
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halimeh rawad ,klim joseph ,aoude lea ,bersaoui marianne ,najib bernard ,saab wiam ,fakhoury fadi ,skaf rana
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منبع
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journal of reproduction and infertility - 2025 - دوره : 26 - شماره : 1 - صفحه:58 -63
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چکیده
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Background: immune thrombocytopenia (itp) is an autoimmune condition that affects individuals of all ages, leading to a heightened risk of bleeding. itp accounts for 5% of all pregnancy-related thrombocytopenia cases with an incidence of 1 in every 1,000 pregnant women. several conditions can cause thrombocytopenia during pregnancy, making the diagnosis challenging. current treatment of patients with itp focuses on maintaining a safe platelet count rather than correcting it to normal levels. case presentation: this article presents a case of a 26-year-old patient at 33 weeks of gestation with severe symptoms of thrombocytopenia, evidenced by a platelet count of 1000/mm 3 . the patient experienced self-resolving episodes of gingival bleeding, vaginal bleeding, and petechiae on her abdomen, as well as on both upper and lower extremities, over a duration of three days. she was successfully managed with prednisolone and intravenous immunoglobulin (ivig), resulting in favorable maternal and neonatal outcomes. conclusion: while there are currently no universally accepted guidelines for the treatment of itp, expert consensus recommendations are available. therefore, treatment should be individualized and closely monitored. a multidisciplinary team approach is essential for the effective management of itp during pregnancy.
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کلیدواژه
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bleeding ,immune thrombocytopenia ,immunoglobulins ,platelet count ,prednisolone ,pregnancy ,purpura
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آدرس
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saint george hospital university medical center, department of obstetrics and gynecology, lebanon. , university of balamand, faculty of medicine and medical sciences, lebanon. , university of balamand, faculty of medicine and medical sciences, lebanon. , saint george hospital university medical center, department of obstetrics and gynecology, lebanon. , centre antoine lacassagne, france. , american university of beirut medical center, department of obstetrics and gynecology, lebanon. , montreuil intercommunal hospital center, department of anesthesia, france. , saint george hospital university medical center, department of obstetrics and gynecology, lebanon.
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Authors
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