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   synthesis of new oxazolam analogues as the anti-anxiety drugs  
   
نویسنده malakpouri gholam reza ,taghizadeh mohammad javad ,ghalkhani masoumeh
منبع journal of applied chemical research - 2021 - دوره : 15 - شماره : 2 - صفحه:65 -72
چکیده    In this research, an efficient synthesis of oxazolam analogues with a number of advantages such as fast  and  cheap  production  procedure  with  great  yields  was  presented.  the  purpose  of  this investigation was to develop a more economical and technically more feasible route to synthesis of oxazolam  analogues.  aminobenzophenone  was  acylated  to  give  corresponding amides.  the  ring forming  reaction  of  amides  with  the  appropriate  amino  (alcohol  or  thiol)  produced  oxazolam analogues with 83-98 % total yield.the structures of synthesized compounds were characterized by recording their ir,1h nmr, 13c nmr, and mass spectra.
کلیدواژه benzodiazepines ,oxazolam analogues ,tricyclic compounds
آدرس university of imam hossein, department of chemistry, iran, university of imam hossein, department of chemistry, iran, shahid rajaee teacher training university, faculty of science, iran
پست الکترونیکی ghalkhani@srttu.edu
 
     
   
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