Electrocatalytic Synthesis of Spirooxindole-Chromene Derivatives in Ethanol/DMSO Media using a Fe-Mn-O Composite as an Efficient Working Electrode

An efficient and sustainable method was developed for electrocatalytic multicomponent synthesisof spirooxindole-chromene derivatives via a green one-pot, three component condensations ofcyclic-1,3-diones, malononitrile and isatins inside an undivided cell where potassium bromidewas applied as electrolyte in ethanol/dmso (95/5 v/v) media, and a practical fe-mn-o compositewas used as cathode electrode. the presented electrosynthesis approach proved to be reliable andcost-effective for the synthesis of target compounds in 83-91% yields. in this method, we highlightthe utility of electrosynthesis method for the preparation of diverse spirooxindole-chromenderivatives that can be a breakthrough for production of vital drugs.