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isolation and complete genome sequencing of zika virus imported from the dominican republic to japan
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نویسنده
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ozawa h. ,tajima s. ,nakayama e. ,kato k. ,yamashita a. ,sekizuka t. ,kuroda m. ,usuku s.
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منبع
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japanese journal of infectious diseases - 2018 - دوره : 71 - شماره : 1 - صفحه:72 -74
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چکیده
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Zika virus (zikv) infection has been documented within central and south america, asia, and africa. here we report the isolation of virus from a patient infected with zikv returning to japan from the dominican republic. the zikv strain was imaged by electron microscopy and its complete genome sequence was analyzed. phylogenetic analysis and molecular characterization revealed that the strain was of asian lineage, and carried 2 unique mutations in its ns5 region. these mutations are characteristic of strains that originated in the dominican republic and the usa in 2016.
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آدرس
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yokohama city institute of public health, department of microbiological testing and research, japan, national institute of infectious diseases, department of virology 1, japan, national institute of infectious diseases, department of virology 1, japan, national institute of infectious diseases, pathogen genomics center, japan, national institute of infectious diseases, pathogen genomics center, japan, national institute of infectious diseases, pathogen genomics center, japan, national institute of infectious diseases, pathogen genomics center, japan, yokohama city institute of public health, department of microbiological testing and research, japan
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Authors
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