Resistance patterns of multidrug resistant acinetobacter baumannii in an ICU of a tertiary care hospital,Malaysia

Backgrounds & objective: antimicrobial resistance is a major health problem worldwide in hospitals. the main contributing factors are exposures to broad-spectrum antimicrobials and cross-infections. understanding the extent and type of antimicrobial use in tertiary care hospitals will aid in developing national antimicrobial stewardship priorities. methods: in this study,we have analyzed the antimicrobial agents’ usage for acquisition of multidrug resistant using retrospective,cross-sectional,single-centre study in a multidisciplinary icu at tertiary care hospital. results: acinetobacter baumannii (acb) was isolated in various specimens from 662 patients. from these,136 patients who were diagnosed with ventilator-associated pneumonia (vap) caused by acb were included into the study. in our study,mdr strain accounts for 51% of all vap cases caused by acb. the development of acb vap were 10.5 + 6.4 days for mdr strains compared to susceptible organism (7.8 + 4.5 days) and had significantly longer icu stay. conclusion: the study concludes that prudent use of antimicrobial agents is important to reduce acquisition of mdr acb. © 2015,pakistan journal of medical sciences. all rights reserved.