Predictive value of elevated neutrophil-lymphocyte ratio for left ventricular systolic dysfunction in patients with non ST-elevated acute coronary syndrome

Objective: we aimed to study the predictive value of the neutrophil-lymphocyte ratio (nlr) for left ventricular systolic dysfunction (lvsd) in patients with non st-elevated acute coronary syndrome (nstacs). methods: a total of 405 patients (mean age 62 years and 75% male) with nst-acs were included in the study. the study population was divided into tertiles based on admission nlr values. the low, medium and high tertiles defined as nlr≤1.81 (n=135), 1.813.2 (n=135), respectively. results: the patients in the high nlr group were older (p<0.001), have higher rate of diabetes mellitus (p=0.028) and non-st elevated myocardial infarction (nstemi) (p<0.001) and have lower left ventricular ejection fraction (lvef) (p<0.001). baseline wbc (p=0.02) and neutrophil (p<0.001) levels and nlr (p<0.001) were significantly higher, baseline hemoglobin (p=0.044), hematocrit (p=0.019) and lymphocyte (p<0.001) levels were significantly lower in the high nlr group. nlr was negatively correlated with lvef in correlation analysis. an nlr >3.2 and age ≥70 were found to be an independent predictor of systolic dysfunction in multivariate analyses. conclusion: an nlr >3.2 is a useful predictor for lvsd in patients with nst-acs. the practice of using an nlr count on admission may be useful for identifying high-risk patients and their associated treatment methods.