Clinical comparison of propofol-remifentanil TCI with sevoflurane induction/maintenance anesthesia in laparoscopic cholecystectomy

Objective: we aimed to compare the anesthetic characteristics between total intravenous anesthesia (tiva) using propofol-remifentanil with target control infusion (tci) and volatile induction and maintenance anesthesia (vima) using sevoflurane and sufentanyl for patients undergoing laparoscopic cholecystectomy. methods: a total of 120 patients undergoing laparoscopic cholecystectomy were randomly assigned to two groups. patients in group t received tci of propofol-remifentanil for induction and maintenance. patients in group s received sevoflurane-sufentanyl for induction and maintenance. results: patients in group s had a significantly faster induction time than patients in group t (109s vs.44s). the emergence time in terms of time to extubation was comparable between the two groups, while the time to eyes opening (419s vs.483s, p=0.006) and duration in pacu were longer in group s (44 min vs.53 min, p=0.017). ten (17.2%) patients in group s were administered an antihypertensive drug when gallbladder issues were present, while only 1(1.7%) patient needed this drug in group t (p=0.004).more patients in group t than in group s received fentanyl for analgesia in pacu (88%vs.70%, p=0.013). the incidence of postoperative nausea and vomiting (ponv) in pacu was higher in group s than in group t (20% vs.38%, p=0.027). conclusion: both techniques had advantages and disadvantages in laparoscopic cholecystectomy; none of the techniques studied was superior.